• MATLAB Online cannot interact with some hardware, including instrument control.  Hardware that can be accessed include:
  
  • MATLAB Online can interact with USB webcams only through Google Chrome.
  • MATLAB Online can communicate with Raspberry Pi hardware.
    
  • MATLAB Online can interact with audio playback devices through Google Chrome.
  • Serialport() not supported in MATLAB Online
• Packaging tools for add-ons and MATLAB Compiler and MATLAB Compiler SDK are not supported.
  
• Windows-specific components like COM are not supported. 
  
• xlsread and xlswrite will work in basic mode.
• Using the MEX command to build C/C++ or Fortran MEX-files is not supported.
• Files larger than 256 MB cannot be uploaded on MATLAB Online, but can be through MATLAB Drive.
• The graphical interface to the profiler is not supported.
• Use of the shell escape bang (!) command is not fully supported.
• App Designer is only available in Google Chrome and Microsoft Edge

Most Simulink features, including editing and simulating models, are supported.

Simulink Online can communicate with Raspberry Pi hardware - external mode is not supported.

Simulink Online can communicate with Parrot Minidrone hardware - deployment is not supported.

Features that are not supported:

• Variant Manager
  
• Simulink Debugger

Other Simulink Online limitations:

• Only Windows^® keyboard shortcuts are supported
• Screen resolutions larger than 1920x1200 are not supported
  
• Users of Simulink Online outside of the US may experience slow performance.

• All features that require Unreal Engine^® (including Simulation 3D library)
• Aerospace Blockset™ Interface for Unreal Engine^® Projects support package
• All features that require FlightGear
• Pilot Joystick and Pilot Joystick All blocks

• aeroDataPackage
• Aero.FGAnimation
• Aero.VirtualRealityAnimation
  

• Audio device I/O (audio device reader and writer, audio I/O in apps and in Simulink)
• MIDI device I/O (midi device and Simulink MIDI controls block)
• Plugin generation (only JUCE project generation is supported)

• RF Propagation functionality

• vision.VideoPlayer System Object
• vision.DeployableVideoPlayer System Object
• Camera Calibrator
• Stereo Camera Calibrator
• Image Labeler
• Video Labeler
• OCR Trainer

• Only supported for SQLite databases

• dsp.AudioFileWriter
  
• audioDeviceWriter
• Filter Builder app
  
• dspunfold

• Support packages that require Embedded Coder

• GPU Coder app
• MATLAB Coder Support Package for NVIDIA Jetson and NVIDIA DRIVE Platforms
• Standalone deep Learning code generation for TensorRT target

• MATLAB: Generating HDL code from MATLAB only supported via command-line API.  HDL Coder app is not supported.
• Simulink: Generating HDL code from Simulink supported via command-line API and Simulink Toolstrip.  HDL Workflow Advisor is not supported.

• Only MQTT supported

• implay
• immovie
• Image Segmenter
• Image Region Analyzer
• Image Batch Processor
  

• Lidar Labeler app
• Lidar-Camera Calibrator app
• Lidar Viewer app
• Lidar Toolbox Support Package for Velodyne LiDAR Sensors
• Lidar Toolbox Support Package for Ouster Lidar Sensors

• MATLAB Coder app
• Standalone deep Learning code generation for MKL-DNN target
• MATLAB Coder Support Package for NVIDIA Jetson and NVIDIA DRIVE Platforms

• Equation reporter's direct renderer is not supported
• No support to programmatically display PPT and DOCX reports

• Medical Image Labeler

• MPC Designer app

• Deployment to hardware
• Host models (models with phrase “host” in the file name)
• Host Serial Receive, Host Serial Setup, and Host Serial Transmit blocks

• Parallel Preferences are not supported
• Local clusters are not available in MATLAB Online

• Radar Designer app

• All features that require a Gazebo Connection are currently not supported for MATLAB Online
• Inverse Kinematics Designer App

• Satellite Link Budget Analyzer App

• trackingGlobeViewer does not support the 'snapshot' object function

• Filter Builder app

• Results Explorer
• Variable Viewer
• Statistics Viewer
• Model table of nominal values

• Block parameters can only be viewed and changed via the API commands get_param and set_param
• Mechanics Explorer

• Model Advisor parallel run
• Metrics Dashboard

• Support packages that require Simulink Coder

• Model Linearizer
• Control System Designer
• Control System Tuner
• Frequency Response Estimator
• Steady State Manager

• Parameter Estimator App
• Response Optimizer App
• Sensitivity Analyzer App

• MuPad Notebook and functions that interface with it

• fastTextWordEmbedding

• Flight Log Analyzer App (flightLogAnalyzer)
• Simulation 3D library in Simulink (uavsim3dlib)
• mavlinkio can only send and receive messages within local host
• UAV Scenario Designer App

• All functionalities interfacing with third-party devices, including physical hardware, virtual channels and SocketCAN channels.
• XCP features in MATLAB and Simulink.

• Simulink: Video Viewer block not supported.  Use Video Display block instead.
• MATLAB: vision.DeployableVideoPlayer not supported.  Use vision.VideoPlayer instead.
• Support packages not supported

• waveletAnalyzer App