In recent years, practical verification methods for large-scale industrial control systems have emerged where simulation is used to verify high-level functional requirements. These simulation-guided verification technologies can be effectively used with a closed-loop simulator such as model-in-the-loop (MIL) or software-in-the-loop (SIL) to verify requirements during the early control design phase. While this simulation-guided method has already produced promising results in some cases where formal methods cannot be applied, gaps between the current capability and expectations have been identified. In this talk, the on-going effort to deploy this new technology at Toyota will be presented.